186 Harmful of effects of GMO – Direct Cancer etc.


186 Health Risks of GM Foods

Section 1: Evidence of reactions in animals and humans

1. GM potatoes damaged rats
2. Rats were fed potatoes engineered to produce their own insecticide.
3. They developed potentially precancerous cell growth in the digestive tract, inhibited development of their brains, livers and testicles, partial atrophy of the liver, enlarged pancreases and intestines and immune system damage.
4. The cause was not the insecticide, but in all likelihood was the process of genetic engineering.
5. GM foods on the market—which were created with the same process—have not been subject to such an extensive testing protocol.

Rats fed GM tomatoes got bleeding stomachs, several died
6. Rats were fed the GM FlavrSavr tomato for 28 days.
7. Seven of 20 rats developed stomach lesions (bleeding stomachs); another 7 of 40 died within two weeks and were replaced in the study.
8. The tomato was approved despite unresolved safety questions by FDA scientists.

 Rats fed Bt corn had multiple health problems
9. Rats were fed Monsanto’s Mon 863 Bt corn for 90 days.
10. They showed significant changes in their blood cells, livers and kidneys, which might indicate disease.
11. Although experts demanded follow-up, Monsanto used unscientific, contradictory arguments to dismiss concerns.

Mice fed GM Bt potatoes had intestinal damage
12. Mice were fed either GM potatoes engineered to produce the Bt-toxin or natural potatoes spiked with Bt-toxin.
13. Both diets created abnormal and excessive cell growth in the lower part of their small intestine (ileum).
14. Similar damage to the human small intestine might result in incontinence or flu-like symptoms, and may be precancerous.
15. This study overturns the assumptions that Bt-toxin is destroyed during digestion and is not biologically active in mammals.

Workers exposed to Bt cotton developed allergies
16. Agricultural laborers in six villages who picked or loaded Bt cotton reported reactions of the skin, eyes and upper respiratory tract.
17. Some laborers required hospitalization.
18. Employees at a cotton gin factory take antihistamines everyday.
19. One doctor treated about 250 cotton laborers

Sheep died after grazing in Bt cotton fields
20.After the cotton harvest in parts of India, sheep herds grazed continuously on Bt cotton plants.
21. Reports from four villages revealed that about 25% of the sheep died within a week.
22. Post mortem studies suggest a toxic reaction.

Inhaled Bt corn pollen may have triggered disease in humans
23. In 2003, approximately 100 people living next to a Bt cornfield in the Philippines developed skin, respiratory, intestinal reactions and other symptoms while the corn was shedding pollen.
24. Blood tests of 39 people showed an antibody response to Bt-toxin, which supports—but does not prove—a link.
25. The symptoms reappeared in 2004 in at least four other villages that planted the same corn variety.
26.Villagers also attribute several animal deaths to the corn.

Farmers report pigs and cows became sterile from GM corn
27. More than 20 farmers in North America report that pigs fed GM corn varieties had low conception rates, false pregnancies or gave birth to bags of water.
28. Both male and female pigs became sterile.
29. Some farmers also report sterility among cows.

gmo food pyramid

Twelve cows in Germany died mysteriously when fed Bt corn
30. Twelve dairy cows died on a farm in Hesse Germany, after being fed a diet with significant amounts of a single GM corn variety, Bt 176.
31. Other cows in the herd had to be killed due to some mysterious illness.
32. Syngenta, the producers of Bt 176, compensated the farmer for part of his losses, but did not admit responsibility for the cow deaths.
33. In spite of demands by the farmer and even public protests, no detailed autopsy reports were made available.

Mice fed Roundup Ready soy had liver cell problems
34. The liver cells of mice fed Roundup Ready soybeans showed significant changes.
35. Irregularly shaped nuclei and nucleoli, an increased number of nuclear pores and other changes, all suggest higher metabolism and altered patterns of gene expression.
36. The changes may be in response to a toxin.
37. Most of the effects disappeared when GM soy was removed from the diet.

Mice fed Roundup Ready soy had problems with the pancreas
38. Mice fed GM soy showed changes in the synthesis and processing of digestive enzymes.
39. The production of alpha-amylase, a major digestive enzyme, dropped by as much as 77%.
40. This, combined with other pancreatic changes, suggests that GM soy may interfere with digestion and assimilation, as well as alter gene expression.

Mice fed Roundup Ready soy had unexplained changes in testicular cells
41. The structure and gene expression pattern of testicle cells of mice fed Roundup Ready soybeans changed significantly.
42. The cause for the changes is unknown, but the testicles are sensitive indicators of toxins.
43. Some of the changes might possibly influence adult fertility as well as the health of the offspring.
44. Mouse embryos from GM-fed mothers did show a temporary decrease in gene expression.

Roundup Ready Soy Changed Cell Metabolism in Rabbit Organs
45. Rabbits fed GM soy for about 40 days showed significant differences in the amounts of certain enzymes in their kidneys, hearts and livers.
46. A rise in LDH1 levels in all three organs suggests an increase in cellular metabolism.
47. Changes in other enzymes point to other alterations in the organs.

Most offspring of rats fed Roundup Ready soy died within three weeks
48. Female rats were fed Roundup Ready soy starting before conception and continuing through pregnancy and weaning.
49. Of the offspring, 55.6% died within three weeks compared to 9% from non-GM soy controls.
50. Some pups from GM-fed mothers were significantly smaller and both mothers and pups were more aggressive.
51. In a separate study, after a lab began feeding rats a commercial diet containing GM soy, offspring mortality reached 55.3%.
52. When offspring from GM-fed rats were mated together, they were unable to conceive.

Soy allergies skyrocketed in the UK, soon after GM soy was introduced
53. In a single year, 1999, soy allergies in the UK jumped from 10% to 15% of the sampled population.
54. GM soy was imported into the country shortly before 1999.
55. Antibody tests verify that some individuals react differently to GM and non-GM soy varieties.
56. GM soy also has an increased concentration of a known allergen

Rats fed Roundup Ready canola had heavier livers
57. The livers of rats fed GM canola were 12-16% heavier than those fed non-GM varieties.
58. The liver is a chemical factory and primary detoxifier for the body.
59. Heavier livers may indicate liver disease or inflammation.
60. If this were caused by oil-soluble toxins, they may be present in canola oil.

Twice the number of chickens died when fed Liberty Link corn
61. The death rate for chickens fed Chardon LL GM corn for 42 days was 7%, compared to 3.5% for controls.
62. GM-fed chickens also had more erratic body weight and food intake, and less weight gain overall.
63. The study was designed so that only huge differences would be statistically significant.
64. The results were therefore dismissed without follow-up.

GM peas generated an allergic-type inflammatory response in mice
65. In advanced tests not normally part of GM crop evaluations, protein produced by GM peas generated a dangerous immune response in mice.
66. That “same” protein, when produced naturally in beans, had no effect.
67. The GM peas produced a subtle, hard-to-detect difference in the way sugar molecules attached to the protein, which likely caused the problem.
68. The response in mice suggested that the GM peas could provoke inflammatory or allergic reactions in humans; commercialization of the peas was therefore cancelled.
69. This type of subtle but dangerous change in the GM protein would rarely, if ever, be detected in the safety assessments typically used to approve GM crops.

Eyewitness reports: Animals avoid GMOs
70. When given a choice, several animals avoided eating GM food.
71. In farmer-run tests, cows and pigs repeatedly passed up GM corn.
72. Animals that avoided GM food include cows, pigs, geese, squirrels, elk, deer, raccoons, mice and rats.

A GM food supplement killed about 100 people and caused 5,000-10,000 to fall sick
73. One brand of the supplement L-tryptophan created a deadly US epidemic in the 1980s
74. The company genetically engineered bacteria to produce the supplement more economically.
75. Their product contained many contaminants, five or six of which were suspected as the cause of the disease.
76. Discovering the epidemic required multiple coincidences, suggesting that adverse reactions to GM foods may be hard to identify.

PART 1: The Documented Health Risks of Genetically Engineered Foods

Section 2: Gene insertion disrupts the DNA and can create unpredictable health problems

77. Foreign genes disrupt the DNA at the insertion site

78. Growing GM crops using tissue culture can create hundreds or thousands of DNA mutations

79. Gene insertion creates genome-wide changes in gene expression

80. The promoter may accidentally switch on harmful genes

81. The promoter might switch on a dormant virus in plants

82. The promoter might create genetic instability and mutations

83. Genetic engineering activates mobile DNA, called transposons, which generate mutations

84. Novel RNA may be harmful to humans and their offspring

85. Roundup Ready soybeans produce unintentional RNA variations

86. Changes in proteins can alter thousands of natural chemicals in plants, increasing toxins or reducing phytonutrients

87. GM crops have altered levels of nutrients and toxins

Section 3: The protein produced by the inserted gene may create problems

88. A gene from a Brazil nut carried allergies into soybeans

89. GM proteins in soy, corn and papaya may be allergens

90. Bt crops may create allergies and illness

91. The Bt in crops is more toxic than the Bt spray

92. StarLink corn’s built-in pesticide has a “medium likelihood” of being an allergen

93.  Pollen-sterilizing barnase in GM crops may cause kidney damage

94. High lysine corn contains increased toxins and may retard growth

95. Cooking high lysine corn may create disease-promoting toxins

96. Disease-resistant crops may promote human viruses and other diseases

Section 4: The foreign protein may be different than what is intended

97. GM proteins may be misfolded or have added molecules

98. Transgenes may be altered during insertion

99. Transgenes may be unstable, and rearrange over time

100. Transgenes may create more than one protein

101. Weather, environmental stress and genetic disposition can significantly change gene expression

102. Genetic engineering can disrupt the complex relationships governing gene expression

Section 5: Transfer of genes to gut bacteria, internal organs, or viruses

103. In spite of industry claims, transgenes survive the digestion system and can wander

104. Transgene design facilitates transfer into gut bacteria

105. Transgenes may proliferate in gut bacteria over the long-term

106. Transgene transfer to human gut bacteria is confirmed

107.  GM foods might create antibiotic-resistant diseases

108.  The promoter can also transfer, and may switch on random genes or viruses

109. If Bt genes transfer, they could turn our gut bacteria into living pesticide factories

110. Genes may transfer to bacteria in the mouth or throat

111.  Transfer of viral genes into gut microorganisms may create toxins and weaken peoples’ viral defenses

Section 6: GM crops may increase environmental toxins and bioaccumulate toxins in the food chain

112. Glufosinate-tolerant crops may produce herbicide “inside” our intestines

113. Herbicide-tolerant crops increase herbicide use and residues in food

114. Tiny amounts of herbicide may act as endocrine disruptors

115. GM crops may accumulate environmental toxins or concentrate toxins in milk and meat of GM-fed animals

116. Disease-resistant crops may promote new plant viruses, which carry risks for humans

Section 7: Other types of GM foods carry risks

117. Milk from rbGH treated cows may increase risk of cancer and other diseases

118. Milk from rbGH-treated cows likely increases the rate of twin births

119.Food additives created from GM microorganisms pose health risks

Section 8: Risks are greater for children and newborns

120. Pregnant mothers eating GM foods may endanger offspring

121. GM foods are more dangerous for children than adults

Section 1: Evidence of reactions in animals and humans

122. GM Potatoes Damages Rats (see full content PDF)

123. Rats Fed GMO Tomatoes got bleeding stomachs, several died

124.  Rats Fed Bt Corn had multiple health problems

125. Mice Fed GM Bt Potatoes had intestinal damage

126. Workers exposed to Bt cotton developed allergies

127. Sheep died after grazing in Bt cotton fields

128. Inhaled Bt corn pollen may have triggered disease in humans

129. Farmers report pigs and cows became sterile from GM corn

130. Twelve cows in Germany died mysteriously when fed Bt corn

131. Mice fed Roundup Ready soy had liver cell problems

132. Mice fed Roundup Ready soy had problems with the pancreas

133. Mice fed Roundup Ready soy had unexplained changes in testicular cells

134. Roundup Ready Soy Changed Cell Metabolism in Rabbit Organs

135. Most offspring of rats fed Roundup Ready soy died within three weeks (see full content PDF)

136. Soy allergies skyrocketed in the UK, soon after GM soy was introduced

137. Rats fed Roundup Ready canola had heavier livers

138. Twice the number of chickens died when fed Liberty Link corn

139. GM peas generated an allergic-type inflammatory response in mice

140. Eyewitness reports: Animals avoid GMOs

141.  A GM food supplement killed about 100 people

Section 2: Gene insertion disrupts the DNA and can create unpredictable health problems

142. Foreign genes disrupt the DNA at the insertion site

143. Growing GM crops using tissue culture can create hundreds or thousands of DNA mutations

144. Gene insertion creates genome-wide changes in gene expression

145. The promoter may accidentally switch on harmful genes

146. The promoter might switch on a dormant virus in plants

147.  The promoter might create genetic instability and mutations

148. Genetic engineering activates mobile DNA, called transposons, which generate mutations

149. Novel RNA may be harmful to humans and their offspring

150. Roundup Ready soybeans produce unintentional RNA variations

151. Changes in proteins can alter thousands of natural chemicals in plants, increasing toxins or reducing phytonutrients

152. GM crops have altered levels of nutrients and toxins

Section 3: The protein produced by the inserted gene may create problems

153. A gene from a Brazil nut carried allergies into soybeans

154.GM proteins in soy, corn and papaya may be allergens

155.Bt crops may create allergies and illness

156. The Bt in crops is more toxic than the Bt spray

157.StarLink corn’s built-in pesticide has a “medium likelihood” of being an allergen

158.Pollen-sterilizing barnase in GM crops may cause kidney damage

159.High lysine corn contains increased toxins and may retard growth

160.Cooking high lysine corn may create disease-promoting toxins

161.Disease-resistant crops may promote human viruses and other diseases

Section 4: The foreign protein may be different than what is intended

162.GM proteins may be misfolded or have added molecules

163.Transgenes may be altered during insertion

164.Transgenes may be unstable, and rearrange over time

165.Transgenes may create more than one protein

166.Weather, environmental stress and genetic disposition can significantly change gene expression

167.Genetic engineering can disrupt the complex relationships governing gene expression

Section 5: Transfer of genes to gut bacteria, internal organs, or viruses

168.In spite of industry claims, transgenes survive the digestion system and can wander

169.Transgene design facilitates transfer into gut bacteria

170.Transgenes may proliferate in gut bacteria over the long-term

171.Transgene transfer to human gut bacteria is confirmed

172.GM foods might create antibiotic-resistant diseases

173.The promoter can also transfer, and may switch on random genes or viruses

174.If Bt genes transfer, they could turn our gut bacteria into living pesticide factories

175.Genes may transfer to bacteria in the mouth or throat

176.Transfer of viral genes into gut microorganisms may create toxins and weaken peoples’ viral defenses

Section 6: GM crops may increase environmental toxins and bioaccumulate toxins in the food chain

177.Glufosinate-tolerant crops may produce herbicide “inside” our intestines

178.Herbicide-tolerant crops increase herbicide use and residues in food

179.Tiny amounts of herbicide may act as endocrine disruptors

180.GM crops may accumulate environmental toxins or concentrate toxins in milk and meat of GM-fed animals

181.Disease-resistant crops may promote new plant viruses, which carry risks for humans

Section 7: Other types of GM foods carry risks

182.Milk from rbGH treated cows may increase risk of cancer and other diseases

183.Milk from rbGH-treated cows likely increases the rate of twin births

184.Food additives created from GM microorganisms pose health risks

Section 8: Risks are greater for children and newborns

185.Pregnant mothers eating GM foods may endanger offspring

186.GM foods are more dangerous for children than adults

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